8-Hydroxyquinoline (8-HQ)
Zogulitsa: 8-Hydroxyquinoline (8-HQ) yokhala ndipamwamba kwambiri
NKHANI #:148-24-3
Molecular Formula: C9H7NO
Zomangamanga:
Ntchito: Mankhwala apakatikati; Mankhwala ophera tizilombo ndi utoto wapakati
Zofotokozera:
| Kanthu | Standard |
| Maonekedwe | Pafupifupi ufa wonyezimira woyera kapena wonyezimira kapena makristasi owoneka bwino |
| Kununkhira | Phenolic |
| Yankho (10% mu alc) | Zomveka bwino |
| Zitsulo zolemera | ≤20ppm |
| Zotsalira pakuyatsa | ≤0.2% |
| Chitsulo | ≤20ppm |
| Mtundu wosungunuka | 72-75 ℃ |
| Chloride | ≤0.004% |
| Sulfate | ≤0.02% |
| Kuyesa | 99-99.8% |
| 5-Hydroxyquinoline | ≤0.2 % |
Kutha
Amasungunuka mu ethanol, acetone, chloroform, benzene ndi mineral acid, pafupifupi osasungunuka m'madzi.
8-hydroxyquinoline ndi amphoteric, sungunuka mu zidulo amphamvu ndi maziko, ionized mu ayoni zoipa m'munsi, womangidwa ma hydrogen ayoni mu zidulo, ndipo ali otsika kwambiri solubility pa pH = 7.
Kugwiritsa ntchito mwachindunji
1. Monga mankhwala apakatikati, sizinthu zokhazokha zopangira kexieling, chloroiodoquinoline ndi paracetamol, komanso zapakati pa utoto ndi mankhwala ophera tizilombo. Mankhwalawa ndi apakati a halogenated quinoline anti amoeba mankhwala, kuphatikizapo quiniodoform, chloroiodoquinoline, diioquinoline, ndi zina zotero. Amathandiza pa kamwazi ya amoeba ndipo alibe mphamvu pa protozoa ya extraintestinal amoeba. Amanenedwa kunja kuti mankhwala amtunduwu angayambitse subacute spinal optic neuropathy, kotero yaletsedwa ku Japan ndi United States. Diioquinoline imayambitsa matendawa mocheperapo kuposa chloroiodoquinoline. 8-hydroxyquinoline ndi mtundu wapakatikati wa utoto ndi mankhwala ophera tizilombo. Mchere wake wa sulphate ndi mkuwa ndiwoteteza kwambiri, mankhwala opha tizilombo komanso anti mildew agents. Chogulitsacho ndi chizindikiro cha complexometric chowunikira mankhwala.
2. Monga chothandizira komanso chotsitsa chamvula komanso kulekanitsa ma ion zitsulo, imatha kulumikizana ndi Cu.+ 2, kukhala+ 2, Mg+ 2, Ca+ 2, Sr+ 2, Ba + 2 ndi zn+ 2,Cd+2,Al+3,Ga+3,In+3,Tl+3,Yt+3,La +3,Pb+2,B+3,Sb+ 3,Cr+3,MOO+ 22. Kusokonezeka kwa Mn+ 2,Fe+ 3, CO+ 2, Ndi+ 2, PD ndi+ 2, CE+ 3, ndi ayoni ena achitsulo. Organic microanalysis, muyezo wa kutsimikiza kwa heterocyclic nitrogen, organic synthesis. Ndiwonso wapakatikati wa utoto, mankhwala ophera tizilombo ndi ma halogenated quinolines. Mchere wake wa sulphate ndi mkuwa ndi woteteza kwambiri.
3. Kuonjezera zomatira za epoxy resin kungathandize kulimbitsa mphamvu zomangira ndi kutentha kukana kukalamba kwazitsulo (makamaka zitsulo zosapanga dzimbiri), ndipo mlingo wake nthawi zambiri ndi 0.5 ~ 3 phr. Ndi mankhwala apakatikati a halogenated quinoline anti amoeba, komanso mankhwala ophera tizilombo ndi utoto. Itha kugwiritsidwa ntchito ngati inhibitor mildew, preservative mafakitale, stabilizer ya polyester resin, phenolic resin ndi hydrogen peroxide, komanso ngati chizindikiritso cha complexometric titration pakuwunika mankhwala.
4. Izi siziri zapakatikati mwa mankhwala a halogenated quinoline, komanso zapakatikati za utoto ndi mankhwala ophera tizilombo. Mchere wake wa sulphate ndi mkuwa ndiwoteteza kwambiri, mankhwala opha tizilombo komanso anti mildew agents. Zomwe zili zovomerezeka (gawo la misa) mu zodzoladzola ndi 0.3%. Zopangira zodzitetezera ku dzuwa ndi mankhwala a ana osapitirira zaka 3 (monga ufa wa talcum) ndizoletsedwa, ndipo "zoletsedwa kwa ana osapitirira zaka 3" zidzasonyezedwa pa chizindikiro cha mankhwala. Pochita ndi mabakiteriya omwe ali pakhungu ndi chikanga cha bakiteriya, gawo lalikulu la 8- hydroxyquinoline mu emulsion ndi 0.001% mpaka 0.02%. Amagwiritsidwanso ntchito ngati mankhwala ophera tizilombo toyambitsa matenda, antiseptic ndi bactericide, ndipo zotsatira zake zotsutsana ndi nkhungu zimakhala zamphamvu. 8- hydroxyquinoline potaziyamu sulfate amagwiritsidwa ntchito mu kirimu wosamalira khungu ndi mafuta odzola (kachigawo kakang'ono) kuchokera ku 0.05% mpaka 0.5%.