Hydroxypropyl methylcellulose HPMC imatha kusintha kwambiri kusunga madzi mumatope.Pamene ndalama zowonjezera ndi 0.02%, chiwerengero chosungira madzi chidzawonjezeka kuchoka pa 83% mpaka 88%;ndalama zowonjezera ndi 0.2%, madzi osungira madzi ndi 97%.Pa nthawi yomweyo, pang'ono HPMC komanso kwambiri amachepetsa stratification ndi magazi mlingo wa matope, zomwe zikusonyeza kuti HPMC akhoza bwino posungira madzi a matope, komanso kwambiri bwino cohesiveness matope, amene kwambiri. zopindulitsa pakufanana kwa kapangidwe kamatope.
Komabe, hydroxypropyl methylcellulose HPMC ili ndi vuto linalake pa mphamvu yosinthasintha komanso mphamvu yopondereza ya matope.Ndi kuwonjezeka kwa kuchuluka kwa kuchuluka kwa HPMC, mphamvu yosinthasintha ndi mphamvu yopondereza ya matope imachepa pang'onopang'ono.Pa nthawi yomweyo, HPMC akhoza kuonjezera kumakoka mphamvu ya matope.Pamene kuchuluka kwa HPMC zosakwana 0.1%, kumakoka mphamvu ya matope kumawonjezeka ndi kuwonjezeka HPMC mlingo.Kuchulukako kukakhala kopitilira 0.1%, kulimba kwamphamvu sikuwonjezeka kwambiri.Hydroxypropyl Methyl
Cellulose HPMC imawonjezeranso mphamvu ya mgwirizano wamatope.0.2% HPMC idakulitsa mphamvu ya mgwirizano wamatope kuchokera ku 0.72 MPa kupita ku 1.16 MPa.
Kafukufuku wasonyeza kuti HPMC akhoza kukulitsa kwambiri nthawi yotsegulira matope, kotero kuti kuchuluka kwa matope akugwa kumachepetsedwa kwambiri, zomwe zimapindulitsa kwambiri pomanga matayala.Pamene HPMC sichikuphatikizidwa, mphamvu ya mgwirizano wa matope imachepetsedwa kuchokera ku 0.72 MPa kufika ku 0.54 MPa pambuyo pa 20mins, ndipo mphamvu ya mgwirizano wa matope ndi 0.05% ndi 0.1% HPMC adzakhala padera 0.8 MPa ndi 0.84 MPa pambuyo pa 20mins.Pamene HPMC si blended, kutsetsereka kwa matope ndi 5.5mm.Ndi kuchuluka kwa zomwe zili mu HPMC, kutsika kumacheperachepera.Pamene mlingo ndi 0.2%, kutsetsereka kwa matope kumachepetsedwa kufika 2.1mm.
Nthawi yotumiza: Mar-03-2022