Kusungunuka kwa HPMC kumaphatikizapo: njira yothetsera madzi ozizira nthawi yomweyo ndi njira yotentha yothetsera, njira yosakaniza ufa ndi njira yonyowetsa zosungunulira.
Njira yamadzi ozizira ya HPMC imathandizidwa ndi glyoxal, yomwe imamwazika mwachangu m'madzi ozizira.Panthawiyi, si njira yeniyeni yothetsera vutoli.Ndilo yankho pamene mamasukidwe akayendedwe ukuwonjezeka.Yankho lotentha silimathandizidwa ndi glyoxal.Pamene voliyumu ya glyoxal ndi yayikulu, imabalalika mwachangu, koma kukhuthala kumawuka pang'onopang'ono.
Popeza HPMC ndi insoluble m'madzi otentha, HPMC akhoza wogawana omwazika m'madzi otentha pa siteji koyamba, ndiyeno mwamsanga kusungunuka pamene utakhazikika.
Njira ziwiri zodziwika bwino zafotokozedwa pansipa:
1) Ikani madzi otentha ofunikira mumtsuko ndikuwotha mpaka 70 ℃.Hydroxypropyl methylcellulose idawonjezeredwa pang'onopang'ono ndikugwedezeka pang'onopang'ono, HPMC idayamba kuyandama pamadzi, kenako pang'onopang'ono kupanga slurry, yomwe idakhazikika pansi pa kugwedezeka.
2) Onjezani 1/3 kapena 2/3 ya madzi ofunikira mumtsuko, kutentha mpaka 70 ℃, kumwaza HPMC molingana ndi njira ya 1) kukonzekera slurry yamadzi otentha;Kenaka yikani madzi ozizira otsala ku slurry yamadzi otentha, yambitsani ndikuziziritsa kusakaniza.
Madzi ozizira pompopompo HPMC imatha kusungunuka powonjezera madzi mwachindunji, koma nthawi yoyamba ya viscosity ndi 1 mpaka 15 mphindi.Nthawi yogwira ntchito siyenera kupitirira nthawi yoyambira.
Njira yosakaniza ufa: ufa wa HPMC umabalalika kwathunthu ndi kusakaniza kowuma ndi zigawo zofanana kapena zambiri za ufa, ndiyeno zimasungunuka ndi madzi.Pankhaniyi, HPMC akhoza kusungunuka popanda caking.
Njira yonyowetsa organic solvent:
Hydroxypropyl methylcellulose imatha kusungunuka pomwaza mu zosungunulira za organic kapena kuzinyowetsa ndi zosungunulira za organic, kenako ndikuwonjezera kumadzi ozizira kapena madzi ozizira.Ethanol, ethylene glycol, etc. angagwiritsidwe ntchito monga zosungunulira organic.
Nthawi yotumiza: Jan-20-2022